Product

Phosphorylated Tau protein IMR Reagent

  • Catalog No. MF-PT1-0060
  • For rapid quantifying phosphorylated Tau protein (pT181) by Immuno Magnetic Reduction (IMR).
Features:
  • Quantify phosphorylated Tau protein (pT181) in the sample easily, rapidly, and accurately
  • Magnetic Nanoparticle
  • Dextran layer
  • For Alzheimer’s disease research and for in-vitro diagnosis use
Description

Use phosphorylated Tau protein (pT181) IMR Reagent only with the XacPro-S System (MagQu Co., Ltd.). The reagent is used to quantitatively measure phosphorylated Tau protein in human fluid specimen, such as plasma, serum or CSF.
Tau protein is a microtubule-associated protein and is abundant in nervous system. Tau protein can maintain the structure of neuron cells and support the transport of substance. When tau proteins phosphorylated, It will result in the self-assembly of tangles in brain and increased some neurodegenerative diseasesincluding Alzheimer’s disease (AD)、Pick's disease、Parkinson's disease (PD)、Progressive supranuclear palsy(PSP) and Corticobasal degeneration (CBD).
The phosphorylated Tau protein (pT181) IMR Reagent is designed for rapid quantifying phosphorylated Tau protein by Immuno Magnetic Reduction (IMR). We conjugated the antibody on the surface of around 50 nm-in-diameter Fe3O4 magnetic particles. When the antibodies on the surface bind with phosphorylated Tau protein (pT181), the magnetic particles form clusters. Therefore, the ac susceptibility (Xac) of magnetic particles would be reduced in the adding ac magnetic field. By measuring the reduction of Xac, we can quantify phosphorylated Tau protein in the sample easily, rapidly, and accurately.

Specification:
Core
Iron Oxide (Fe3O4)
Layer
Dextran
Surface protein
Anti-pTau antibody
Mean Diameter of Particles
50 ~ 60 nm
The analytical range of reagent
0.002 to 10000 pg /mL pTau protein
Buffer
ddH2O
Storage temp.
2 ~ 8 ℃
Ordering information:
Catalog Number Description Package Size
MF-PT1-0060 50 tests 1 mL x 4
Applications:
  • Applications Content: 
    Quantitative detection for ultra-low-concentration bio-molecules, e.g. Alzheimer's-disease bio-markers in blood.